Metabolisme Lipid (Blok 2 Biomedik 1)

METABOLISME LIPID
    Asam lemak :  R- CH2 – COOH

         C H3 – COOH             CH3 – CH2 – COOH    
             Asam asetat           Asam propionat
                               10    9                                                                    
          CH3 – (CH2)7 – CH = CH – (CH2)7 – COOH.
               Asam oleat             (18:1,9)



Cw          2        3       4      5
CH3 – CH2 – C H= CH - C H2 – C H2 – C H2 -C H2… …-  C – C – COOH.

Lemak Netral (Triasilgliserol/Trigliserida)  :
Contoh:                       O
                                   ║
                 CH2 – O – C – C15H31 
                 |                O
                  |                ║
                 CH –  O – C –  C17H35
                 |               O                        DIPALMITOSTEARIN                              
                 |               ║
                 CH2 –O – C – C15H31


 Rumus  :    Contoh Phospholipid :
                             Phosphatidil Etanolamin

                                                  O
                                                   ║
                                 CH2 – O – C – C15H31            (C15H31 =R1)                                                                  
                                 |               O
                                 |               ║
                                CH – O – C – C17H35              (C17H35  = R2)                                                
                                 |                 O
                                 |                 ║                                                                                                      
                                CH2 – O – C – O – P – O - CH2  - CH2 – NH3 
                            
                                                               O-

                                             Residu phosphat.      etanolamin

Asetil KoA hasil b-oksidasi:
*asetil KoA =>(oksidasi) CO2 + H2O.(melalui TCA)
*Bahan sintesis kolesterol dan steroid.
*Dalam hati membentuk badan-badan keton : sebagai sumber energi bagi starvasi lama.                



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